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Polyvinylpyrrolidone K30 (PVP K30)

PVP K30 has a wide range of applications in the pharmaceutical field, and is one of the three internationally advocated pharmaceutical excipients. Its most common use as a binder for tablet and granule formulations. PVP K30 can also be used as a flow aid for capsules, a detoxifying agent and lubricant for ophthalmic drugs, a solubilizer for injectable formulations, a dispersant for liquid formulations, and a stabilizer for enzymes and heat-sensitive drugs. PVP K30 can also be combined with iodine to produce PVP-I disinfectants.
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About Polyvinylpyrrolidone K30:

High temperature stability: PVP K30 can work for a long time at temperatures as high as 250°C, demonstrating excellent resistance to high temperatures. It does not melt or decompose, making it suitable for use in extreme hot environments.

Chemical resistance: PVP K30 exhibits outstanding resistance to chemical corrosion, able to withstand attacks from various acids, alkalis, and solvents. It can be used in harsh environments such as acidic, alkaline, and organic solvent.

Friction resistance: PVP K30 possesses good friction resistance, reducing wear and bonding between mechanical components.

Biocompatibility: PVP K30 is biocompatible and causes no irritation or toxicity to the human body and tissues.


Applications of Polyvinylpyrrolidone K30:

Pharmaceutical Industry: 

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Binder in Tablets and Capsules: PVP K30 is widely used as a binder in tablet formulations, helping to hold the ingredients of the tablet together in a solid form. It ensures that tablets and capsules are hard enough to handle without breaking during packaging, shipping, and everyday use, yet capable of disintegrating properly in the body.

Solubilizer: PVP K30 helps in increasing the solubility of poorly soluble drugs, enhancing their bioavailability. By forming complexes with drugs, PVP K30 can improve the dissolution rate of drugs in the gastrointestinal tract, thereby enhancing their absorption and effectiveness.

Disintegrant: PVP K30 can act as a disintegrant in low concentrations, helping tablets and capsules to break apart in the digestive tract, which is essential for the release and absorption of the medication.

Film Former: In topical, ophthalmic, and transdermal drug delivery systems, PVP K30 is used as a film-forming agent. It forms a film over the application area, which can be beneficial for wound dressings, drug patches, and ocular solutions, providing a protective barrier or controlled drug release.

Stabilizer: PVP K30 is used to stabilize suspensions and emulsions in pharmaceutical formulations, preventing the active ingredients from degrading or precipitating out of solution. This ensures the stability and efficacy of the medication over its shelf life.

Thickening Agent: It can act as a viscosity-increasing agent in liquid formulations, improving the texture and flow properties of syrups, gels, and liquid suspensions.

Bioadhesion: In some drug delivery systems, such as buccal patches or tablets, PVP K30 can enhance bioadhesion to mucosal surfaces, improving the residence time and absorption of the drug.

Cryoprotectant: In lyophilized (freeze-dried) pharmaceuticals, PVP K30 can protect sensitive molecules from degradation during the freezing and drying processes, preserving their structure and activity.


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Agricultural & Food Industry: 

As a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating; In the wine industry PVO K30 as a fining agent for white wine and some beers.



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Technical Industry: 

As a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper.






pvp7Other uses: 

PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.



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